300 jobs are to go at Didcot-based RM Education.
According to the Oxford Mail, this is the second round of redundancies in the last two years.
Before the first round of redundancies, RM had over 1,200 staff but that number is now 960.
But according to the report, RM has no plans to move out of its headquarters. The company was hit when the British government axed the Building Schools for the Future scheme, instituted by the former Labour government.
RM, formerly known as Research Machines, was started when its founders sold components. It moved on to make PCs, primarily aimed at the educational market, but in more recent times has specialised in providing software for the educational market.